Coating in a Spouted Bed by Rapid Expansion of Supercritical Fluid Solutions.
نویسندگان
چکیده
منابع مشابه
Modeling and Simulation of Rapid Expansion of Supercritical Solutions
Rapid expansion of supercritical solution (RESS) is a promising technique for microparticle production. The literature points out that the RESS technique can be applied to process a wide range of materials including ceramics, polymers, biopolymers, pharmaceutics, and organic compounds. In order to achieve an adequate understanding of the RESS process, it is necessary to conduct more comprehensi...
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Separation of a racemic mixture of ibuprofen at a low concentration level by supercritical fluid chromatography in a simulated moving bed (SFC-SMB) is investigated by simulation. The feasibility of ibuprofen enantiomers separation has been experimentally examined in the literature. Our simulation results show that separation of ibuprofen enantiomers is feasible by this method, and R-ibuprofen a...
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BACKGROUND Supercritical fluid chromatography (SFC) is continually gaining attention in the separation sciences as demand increases for higher throughput isolations and purifications. The higher flow rates associated with SFC provide a significant decrease in analysis time and increase in sample-throughput efficiency. Peptides are of particular interest for SFC due, in part, to the rather exten...
متن کاملDrug Nano-Particles Formation by Supercritical Rapid Expansion Method; Operational Condition Effects Investigation
Dissolution pressure and nozzle temperature effects on particle size and distribution were investigated for RESS (Rapid Expansion of Supercritical Solution) process. Supercritical CO2 was used as solvent and Ibuprofen was applied as the model component in all runs. The resulting Ibuprofen nano-particles (about 50 nm in optimized runs) were analyzed by SEM and laser diffraction pa...
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Article history: As a poorly water-soluble d Received 20 December 2007 Received in revised form 16 May 2008 Accepted 13 June 2008 Available online 25 June 2008
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ژورنال
عنوان ژورنال: KAGAKU KOGAKU RONBUNSHU
سال: 1994
ISSN: 0386-216X,1349-9203
DOI: 10.1252/kakoronbunshu.20.248